Phenotypes associated with this allele
Allelic Composition |
Fn1tm1Bwg/Fn1tm1Bwg
|
|
Genetic Background |
involves: 129S4/SvJae * BALB/c * C57BL/6J |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fn1tm1Bwg mutation
(1 available);
any
Fn1 mutation
(129 available)
|
|
|
neoplasm
N |
• no difference in tumor growth is seen after injection of C57BL/6 melanoma cells
|
cardiovascular system
N |
• no difference in physiological or tumor angiogenesis is seen
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fn1tm1Bwg mutation
(1 available);
any
Fn1 mutation
(129 available)
|
|
|
immune system
N |
• wound healing and peripheral blood leukocyte counts are normal
|
normal phenotype
|
• homozygotes are healthy and fertile
|
neoplasm
|
• the number of angiogenic islets and tumor progression are not different from Tg(RIP1-Tag)2Dh hemizygotes
|
cardiovascular system
N |
• no difference in tumor angiogenesis is seen
|
cardiovascular system
|
• on a high fat high cholesterol diet double homozygous mutants have reduced lesion area compared to Apoetm1Bres homozygotes
|
homeostasis/metabolism