Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasntm1Schi mutation
(0 available);
any
Fasn mutation
(88 available)
|
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|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasntm1Schi mutation
(0 available);
any
Fasn mutation
(88 available)
|
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mortality/aging
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• death at the blastocyst stage, most dying before E3.5
• feeding breeders a diet rich in saturated fatty acids does not prevent lethality of homozygotes
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Allelic Composition |
Fasntm1Schi/Fasn+
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Genetic Background |
129S7/SvEvBrd-Fasntm1Schi |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasntm1Schi mutation
(0 available);
any
Fasn mutation
(88 available)
|
|
|
mortality/aging
|
• Background Sensitivity: 60-90% loss of pups on a 129S7/SvEvBrd background
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Allelic Composition |
Fasntm1Schi/Fasn+
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Genetic Background |
involves: 129S7/SvEvBrd * C57BL/6J |
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fasntm1Schi mutation
(0 available);
any
Fasn mutation
(88 available)
|
|
|
mortality/aging
|
• Background Sensitivity: 60-70% loss of pups on a mixed background involving 129S7/SvEvBrd and C57BL/6J
• feeding breeders a diet rich in saturated fatty acids does not prevent lethality of heterozygotes
|