Phenotypes associated with this allele

• Allele Symbol: Bcl2a1a^tm1Prys
• Allele Name: targeted mutation 1, Michael Prystowsky
• Allele ID: MGI:2656326
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bcl2a1a^tm1Prys/Bcl2a1a^tm1Prys	involves: 129/Sv * C57BL/6J * SJL	MGI:2656328

Genotype
MGI:2656328

hm1

• Allelic Composition: Bcl2a1a^tm1Prys/Bcl2a1a^tm1Prys
• Genetic Background: involves: 129/Sv * C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to induced morbidity/mortality ( J:74478 )

• mutants survive one day longer than wild-type after Toxoplasma gondii infection

immune system

abnormal neutrophil physiology ( J:74478 )

• sporadic increase in apoptosis in inflammatory neutrophils after Toxoplasma gondii infection

decreased inflammatory response ( J:74478 )

• inflammation in attenuated in response to Toxoplasma gondii infection

decreased susceptibility to parasitic infection ( J:74478 )

• peritoneal leukocytosis is decreased in Toxoplasma gondii infected mutants, however no differences in peritoneal parasite load is observed

hematopoietic system

abnormal neutrophil physiology ( J:74478 )

• sporadic increase in apoptosis in inflammatory neutrophils after Toxoplasma gondii infection