hm1

App^tm1Cep/App^tm1Cep
involves: 129S1/Sv * 129X1/SvJ

Key:
♀	phenotype observed in females	WTSI	Wellcome Trust Sanger Institute
♂	phenotype observed in males	Euro	Europhenome
N	normal phenotype

cellular

abnormal cell physiology ( J:35500 )

• increased amyloidogenic processing of App

Mouse Models of Human Disease		OMIM ID	Ref(s)
Alzheimer Disease; AD		104300	J:35500

ht2

App^tm1Cep/App⁺
involves: 129S1/Sv * 129X1/SvJ

Key:
♀	phenotype observed in females	WTSI	Wellcome Trust Sanger Institute
♂	phenotype observed in males	Euro	Europhenome
N	normal phenotype

cellular

abnormal cell physiology ( J:35500 )

• increased amyloidogenic processing of App

Mouse Models of Human Disease		OMIM ID	Ref(s)
Alzheimer Disease; AD		104300	J:35500