Phenotypes associated with this allele

• Allele Symbol: Htr7^tm1Sut
• Allele Name: targeted mutation 1, J Gregor Sutcliffe
• Allele ID: MGI:2450732
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Htr7^tm1Sut/Htr7^tm1Sut	B6.129X1-Htr7^tm1Sut	MGI:2450733

Genotype
MGI:2450733

hm1

• Allelic Composition: Htr7^tm1Sut/Htr7^tm1Sut
• Genetic Background: B6.129X1-Htr7^tm1Sut

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal body temperature homeostasis ( J:81842 )

• lack of hypothermic response following injection with 5-hydroxytryptamine (5 mg/kg)

• lack of hypothermic response following injection with low dosage of 5-carboxamidotryptamine (0.5 mg/kg)

• significant decrease in body temperature following injection with high dosage of 5-carboxamidotryptamine (3 mg/kg)

• decreased hypothermic response following injection with a combination of oleamide (1 mg/kg) and 5-hydroxytryptamine (5 mg/kg)