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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(PSEN1)S8-4Dbo
transgene insertion S8-4, David R Borchelt
MGI:2447452
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Tg(APP695)3Dbo/0
Tg(PSEN1)S8-4Dbo/0		 involves: C57BL/6J * C3H/HeJ MGI:3663623


Genotype
MGI:3663623
cx1
Allelic
Composition		 Tg(APP695)3Dbo/0
Tg(PSEN1)S8-4Dbo/0
Genetic
Background		 involves: C57BL/6J * C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(APP695)3Dbo mutation (3 available)
Tg(PSEN1)S8-4Dbo mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:43788 )
N
• no immunoreactive amyloid beta deposits found in cortex or hippocampus from 9 or 12 month old mice as compared to double transgenic mice: Tg(APP695)3Dbo/0, Tg(PSEN1)5Dbo/0




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Send questions and comments to User Support. 		last database update
06/13/2017
MGI 6.10 		The Jackson Laboratory