Mouse Genome Informatics
hm1
    Arhgap6/Hccs/Mid1tm1Hzo/Arhgap6/Hccs/Mid1tm1Hzo
involves: 129S7/SvEvBrd
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype


Mouse Genome Informatics
cn2
    Arhgap6/Hccs/Mid1tm1Hzo/Arhgap6/Hccs/Mid1tm1Hzo
Tg(EIIa-cre)C5379Lmgd/?

involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 15 of 21 embryos abnormal at E9.5 and E10.5
• mosaic animals were present and were healthy and fertile
• no homozygous mice born

embryogenesis
• many embryos undergoing resorption by E9.5-E10.5
• gastrulation defects

growth/size/body


Mouse Genome Informatics
cn3
    Arhgap6/Hccs/Mid1tm1Hzo/Y
Tg(EIIa-cre)C5379Lmgd/?

involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no hemizygous mice born
• 15 of 21 embryos abnormal at E9.5 and E10.5
• mosaic animals were present and were healthy and fertile

embryogenesis
• many embryos undergoing resorption by E9.5-E10.5
• gastrulation defects

growth/size/body


Mouse Genome Informatics
cn4
    Arhgap6/Hccs/Mid1tm1Hzo/Mid1+
Tg(EIIa-cre)C5379Lmgd/?

involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• no heterozygotes born


Mouse Genome Informatics
ot5
    Arhgap6/Hccs/Mid1tm1Hzo/Y
involves: 129S7/SvEvBrd
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype