All Phenotypes M6pr<tm1Psa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

M6pr^tm1Psa
targeted mutation 1, Paul Saftig
MGI:2429535

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	M6pr^tm1Psa/M6pr^tm1Psa	involves: 129P2/OlaHsd * C57BL/6	MGI:3619606
hm2	M6pr^tm1Psa/M6pr^tm1Psa	involves: 129P2/OlaHsd * C57BL/6J	MGI:3581054

Allelic Composition	M6pr^tm1Psa/M6pr^tm1Psa
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
M6pr^tm1Psa mutation (1 available); any M6pr mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal enzyme/coenzyme level ( J:106558 )

• beta-D-galactosidase, N-acetylglucosaminidase and alpha-D-mannosidase levels in spermatazoa show increases of 17, 63 and 51% respectively in homozygous mutants

Allelic Composition	M6pr^tm1Psa/M6pr^tm1Psa
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
M6pr^tm1Psa mutation (1 available); any M6pr mutation (25 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, incomplete penetrance ( J:16151 )

• fewer than expected homozygotes produced

• normal phenotype otherwise

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