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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Pmp22)247Ueli
transgene insertion 247, Ueli Suter
MGI:2183755
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Pmp22)247Ueli/0 involves: C3H * C57BL/6 MGI:3794450


Genotype
MGI:3794450
tg1
Allelic
Composition
Tg(Pmp22)247Ueli/0
Genetic
Background
involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• Schwann cell density is increased from P21 onwards compared to in wild-type mice
• Schwann cell density is increased from P21 onwards compared to in wild-type mice
• however, Schwann cell proliferation is normal at P21
• beginning at P4, Schwann cell apoptosis rates are double wild-type rates
• mice exhibit almost complete amyelination

Mouse Models of Human Disease
OMIM ID Ref(s)
Charcot-Marie-Tooth Disease, Demyelinating, Type 1A; CMT1A 118220 J:98118





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory