About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ezh2tm1Jnw
targeted mutation 1, Thomas Jenuwein
MGI:2182844
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ezh2tm1Jnw/Ezh2tm1Jnw involves: 129P2/OlaHsd MGI:3035988


Genotype
MGI:3035988
hm1
Allelic
Composition
Ezh2tm1Jnw/Ezh2tm1Jnw
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ezh2tm1Jnw mutation (0 available); any Ezh2 mutation (53 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygous embryos die between E7.5 and E10.5

embryo
• some embryos exhibit a failure of the ICM to grow in culture
• some embryos initiate but do not complete gastrulation
• homozygous embryos are described as growth retarded
• a reduced amount of embryonic tissue was present
• increased amounts of extraembryonic tissue were present

growth/size/body
• homozygous embryos are described as growth retarded

cellular
• some embryos exhibit a failure of the ICM to grow in culture





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/03/2020
MGI 6.15
The Jackson Laboratory