Phenotypes associated with this allele

• Allele Symbol: Enpep^tm1Mdc
• Allele Name: targeted mutation 1, Max D Cooper
• Allele ID: MGI:2182774
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Enpep^tm1Mdc/Enpep^tm1Mdc	involves: 129P2/OlaHsd * C57BL/6	MGI:3618524

Genotype
MGI:3618524

hm1

• Allelic Composition: Enpep^tm1Mdc/Enpep^tm1Mdc
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:47424 )

N • homozygotes are viable, fertile and overtly normal, with no morphological differences in heart, kidney, spleen, brain, ovary, or testis histology

N • importantly, homozygotes display normal B and T cell development, with no significant differences in Ab responses to both thymus-dependent and -independent Ags, serum Ig levels, B lymphopoiesis in fetal liver cultures or in proliferative responses of bone marrow cells to IL-7 and LPS