Mouse Genome Informatics
hm1
    Zfpm2tm1Jml/Zfpm2tm1Jml
involves: 129X1/SvJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging

cardiovascular system
• large atrioventricular canal-type atrial septal defect
• display a single, poorly formed, L-sided common atrioventricular valve that connects both atria to the left ventricle
• the compact zone of the left ventricle myocardium is thinner
• smaller size of the right ventricle cavity
• pulmonic outflow tract is longer, hyperplastic, and narrowed
• position of the aortic outflow tract is abnormal, with a longer length and unusual shape behind the right ventricle
• rightward displacement of the aortic valve
• pulmonary valve is longer, hyperplastic, and thickened
• thickened pulmonic valve
• narrowing of the pulmonic outflow tract

homeostasis/metabolism
• subcutaneous edema

integument
• subcutaneous edema

Mouse Models of Human Disease
OMIM IDRef(s)
Tricuspid Atresia 605067 J:63121


Mouse Genome Informatics
cx2
    Atoh8tm1.1Mlkn/Atoh8tm1.1Mlkn
Zfpm2tm1Jml/Zfpm2+

involves: 129 * 129X1/SvJ * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging
N
• viable and present at the expected Mendelian ratio at P1 and P14 (J:203454)