mortality/aging

• die between E13 and E14

cardiovascular system

abnormal heart development ( J:63121 )

abnormal heart atrium morphology ( J:63121 )

dilated heart atrium ( J:63121 )

complete atrioventricular septal defect ( J:63121 )

• large atrioventricular canal-type atrial septal defect

abnormal heart valve morphology ( J:63121 )

tricuspid valve atresia ( J:63121 )

common atrioventricular valve ( J:63121 )

• display a single, poorly formed, L-sided common atrioventricular valve that connects both atria to the left ventricle

abnormal heart ventricle morphology ( J:63121 )

thin ventricle myocardium compact layer ( J:63121 )

• the compact zone of the left ventricle myocardium is thinner

ventricular septal defect ( J:63121 )

• smaller size of the right ventricle cavity

abnormal pulmonary valve morphology ( J:63121 )

• pulmonary valve is longer, hyperplastic, and thickened

thick pulmonary valve ( J:63121 )

• thickened pulmonic valve

• narrowing of the pulmonic outflow tract

• pulmonic outflow tract is longer, hyperplastic, and narrowed

• position of the aortic outflow tract is abnormal, with a longer length and unusual shape behind the right ventricle

abnormal aortic valve morphology ( J:63121 )

• rightward displacement of the aortic valve

pericardial edema ( J:63121 )

congestive heart failure ( J:63121 )

homeostasis/metabolism

pericardial edema ( J:63121 )

skin edema ( J:63121 )

• subcutaneous edema

integument

skin edema ( J:63121 )

• subcutaneous edema

Mouse Models of Human Disease		OMIM ID	Ref(s)
Tricuspid Atresia		605067	J:63121