All Phenotypes Stat5b<tm1Jni> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Stat5b^tm1Jni
targeted mutation 1, James N Ihle
MGI:2181609

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stat5b^tm1Jni/Stat5b^tm1Jni	either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ)	MGI:3578100

Allelic Composition	Stat5b^tm1Jni/Stat5b^tm1Jni
Genetic Background	either: (involves: 129P2/OlaHsd) or (involves: 129X1/SvJ)

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat5b^tm1Jni mutation (0 available); any Stat5b mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

adipose tissue

abnormal fat pad morphology ( J:77412 )

• reduced in size

growth/size/body

decreased body weight ( J:77412 )

• weight reduced 20-30% relative to controls

liver/biliary system

abnormal liver physiology ( J:77412 )

• a significant decrease in the expression of Major Urinary Protein expression in females

endocrine/exocrine glands

abnormal mammary gland physiology ( J:77412 )

• reduced levels of alpha-lactalbumin and whey acidic protein

integument

abnormal mammary gland physiology ( J:77412 )

• reduced levels of alpha-lactalbumin and whey acidic protein

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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