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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Serpind1tm1Toll
targeted mutation 1, Douglas M Tollefsen
MGI:2179102
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Serpind1tm1Toll/Serpind1tm1Toll involves: 129X1/SvJ * C57BL/6 MGI:3037644
ht2
 		Serpind1tm1Toll/Serpind1tm1Moto involves: 129X1/SvJ * C57BL/6 * CBA MGI:3713847


Genotype
MGI:3037644
hm1
Allelic
Composition		 Serpind1tm1Toll/Serpind1tm1Toll
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Serpind1tm1Toll mutation (2 available); any Serpind1 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased susceptibility to induced thrombosis ( J:74337 )
• formation of an occlusive thrombus in the carotid artery occurs more rapidly after photochemically induced endothelial injury than in normal controls




Genotype
MGI:3713847
ht2
Allelic
Composition		 Serpind1tm1Toll/Serpind1tm1Moto
Genetic
Background		 involves: 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Serpind1tm1Moto mutation (0 available); any Serpind1 mutation (21 available)
Serpind1tm1Toll mutation (2 available); any Serpind1 mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:122173 )
N
• mice are born at or close to the expected Mendelian frequency (~25%), compared to homozygotes for Serpind1tm1Moto allele when heterozygotes for each Serpind1 allele are bred




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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory