Mouse Genome Informatics
hm1
    Nyxnob/Nyxnob
BALB/c-Nyxnob
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• does not display electroretinographic (ERG) b-waves
• ERG finding is observed by day 18
• light-adapted cone ERG retains a negative polarity
• dark-adapted rod ERG retains a negative polarity even with increasing stimulus intensity
• no response to visual evoked potential at flash onset and slight response at flash offset
• decreased light sensitivity

Mouse Models of Human Disease
OMIM IDRef(s)
Night Blindness, Congenital Stationary, Type 1A; CSNB1A 310500 J:50824


Mouse Genome Informatics
hm2
    Nyxnob/Nyxnob
involves: BALB/cGr
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control
• implicit time of the b-wave is delayed
• cone ERG amplitude has a distinctive waveform as compared to control
• b-wave is absent in dark-adapted electroretinogram (ERG)


Mouse Genome Informatics
ht3
    Nyxnob/Nyx+
involves: BALB/cGr
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• reduced b-wave in dark-adapted mice


Mouse Genome Informatics
ot4
    Nyxnob/Y
involves: BALB/cGr
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• implicit time of the b-wave is delayed
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control
• cone ERG amplitude has a distinctive waveform as compared to control
• b-wave is absent in dark-adapted electroretinogram (ERG)