Mouse Genome Informatics
hm1
    Nyxnob/Nyxnob
BALB/c-Nyxnob
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
vision/eye
• does not display electroretinographic (ERG) b-waves (J:50824)
• ERG finding is observed by day 18 (J:50824)
• light-adapted cone ERG retains a negative polarity (J:50824)
• dark-adapted rod ERG retains a negative polarity even with increasing stimulus intensity (J:50824)
• no response to visual evoked potential at flash onset and slight response at flash offset (J:50824)
• decreased light sensitivity (J:81028)

Mouse Models of Human Disease
OMIM IDRef(s)
Night Blindness, Congenital Stationary, Type 1A; CSNB1A 310500 J:50824


Mouse Genome Informatics
hm2
    Nyxnob/Nyxnob
involves: BALB/cGr
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
vision/eye
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control (J:123811)
• implicit time of the b-wave is delayed (J:123811)
• cone ERG amplitude has a distinctive waveform as compared to control (J:123811)
• b-wave is absent in dark-adapted electroretinogram (ERG) (J:123811)


Mouse Genome Informatics
ht3
    Nyxnob/Nyx+
involves: BALB/cGr
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
vision/eye
• reduced b-wave in dark-adapted mice (J:209941)


Mouse Genome Informatics
ot4
    Nyxnob/Y
involves: BALB/cGr
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
vision/eye
• implicit time of the b-wave is delayed (J:123811)
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control (J:123811)
• cone ERG amplitude has a distinctive waveform as compared to control (J:123811)
• b-wave is absent in dark-adapted electroretinogram (ERG) (J:123811)