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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Nyxnob
no b wave
MGI:2177945
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Nyxnob/Nyxnob BALB/c-Nyxnob MGI:3055970
hm2
Nyxnob/Nyxnob involves: BALB/cGr MGI:3720062
ht3
Nyxnob/Nyx+ involves: BALB/cGr MGI:5568984
ot4
Nyxnob/Y involves: BALB/cGr MGI:3720065


Genotype
MGI:3055970
hm1
Allelic
Composition
Nyxnob/Nyxnob
Genetic
Background
BALB/c-Nyxnob
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• does not display electroretinographic (ERG) b-waves (J:50824)
• ERG finding is observed by day 18 (J:50824)
• does not display electroretinographic (ERG) b-waves (J:50824)
• ERG finding is observed by day 18 (J:50824)
• light-adapted cone ERG retains a negative polarity (J:50824)
• light-adapted cone ERG retains a negative polarity (J:50824)
• dark-adapted rod ERG retains a negative polarity even with increasing stimulus intensity (J:50824)
• dark-adapted rod ERG retains a negative polarity even with increasing stimulus intensity (J:50824)
• no response to visual evoked potential at flash onset and slight response at flash offset (J:50824)
• no response to visual evoked potential at flash onset and slight response at flash offset (J:50824)
• decreased light sensitivity (J:81028)
• decreased light sensitivity (J:81028)

Mouse Models of Human Disease
OMIM ID Ref(s)
Night Blindness, Congenital Stationary, Type 1A; CSNB1A 310500 J:50824




Genotype
MGI:3720062
hm2
Allelic
Composition
Nyxnob/Nyxnob
Genetic
Background
involves: BALB/cGr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control (J:123811)
• implicit time of the b-wave is delayed (J:123811)
• cone ERG amplitude has a distinctive waveform as compared to control (J:123811)
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control (J:123811)
• implicit time of the b-wave is delayed (J:123811)
• cone ERG amplitude has a distinctive waveform as compared to control (J:123811)
• b-wave is absent in dark-adapted electroretinogram (ERG) (J:123811)
• b-wave is absent in dark-adapted electroretinogram (ERG) (J:123811)




Genotype
MGI:5568984
ht3
Allelic
Composition
Nyxnob/Nyx+
Genetic
Background
involves: BALB/cGr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• reduced b-wave in dark-adapted mice (J:209941)
• reduced b-wave in dark-adapted mice (J:209941)




Genotype
MGI:3720065
ot4
Allelic
Composition
Nyxnob/Y
Genetic
Background
involves: BALB/cGr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• implicit time of the b-wave is delayed (J:123811)
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control (J:123811)
• cone ERG amplitude has a distinctive waveform as compared to control (J:123811)
• implicit time of the b-wave is delayed (J:123811)
• light adapted ERG is reduced in amplitude and has slower kinetics as compared to control (J:123811)
• cone ERG amplitude has a distinctive waveform as compared to control (J:123811)
• b-wave is absent in dark-adapted electroretinogram (ERG) (J:123811)
• b-wave is absent in dark-adapted electroretinogram (ERG) (J:123811)





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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory