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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Chst3tm1Tmu
targeted mutation 1, Takashi Muramatsu
MGI:2176247
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Chst3tm1Tmu/Chst3tm1Tmu involves: 129S2/SvPas MGI:5615634
hm2
Chst3tm1Tmu/Chst3tm1Tmu involves: 129S2/SvPas * 129X1/SvJ MGI:2663202


Genotype
MGI:5615634
hm1
Allelic
Composition
Chst3tm1Tmu/Chst3tm1Tmu
Genetic
Background
involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chst3tm1Tmu mutation (1 available); any Chst3 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system

immune system

nervous system
• hearing impaired prepulse inhibition

behavior/neurological
• less aggressive in social dominance

endocrine/exocrine glands

hematopoietic system

skeleton
• increased frequency of CD5+ cells in bone marrow




Genotype
MGI:2663202
hm2
Allelic
Composition
Chst3tm1Tmu/Chst3tm1Tmu
Genetic
Background
involves: 129S2/SvPas * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chst3tm1Tmu mutation (1 available); any Chst3 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• reduction in number of naive T cells in the spleen of 5-6 week old mutant animals
• however, normal spleen morphology and lymphocyte trafficking into secondary lymph nodes

nervous system
N
• normal brain development and morphology, particularly the organization of the cerebral cortex and orientation of processes for pyramidal cells

hematopoietic system
• reduction in number of naive T cells in the spleen of 5-6 week old mutant animals
• however, normal spleen morphology and lymphocyte trafficking into secondary lymph nodes





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last database update
12/13/2017
MGI 6.11
The Jackson Laboratory