Analysis Tools
mortality/aging
|
• die around E10.5 and E13.5
|
embryo
|
• exhibit defects in vascular development of the yolk sac
• the two endothelial cell layers are partially detached from the mesothelial and endodermal cell layers and the contacts of the two endothelial layers are not complete, resulting in distended capillary vessel formation
|
|
• shows mild growth retardation at E9.5 that is markedly increased at E10.5 and E11.5
|
pale yolk sac
(
J:73414
)
|
• yolk sac shows severe anemia by E9.5
|
|
• yolk sacs at E9.5 exhibit defects in hematopoiesis
• exhibit fewer blood cells in the space between the endothelial layers of yolk sacs
|
growth/size/body
|
• shows mild growth retardation at E9.5 that is markedly increased at E10.5 and E11.5
|
hematopoietic system
|
• yolk sacs at E9.5 exhibit defects in hematopoiesis
• exhibit fewer blood cells in the space between the endothelial layers of yolk sacs
|
cardiovascular system
|
• exhibit defects in vascular development of the yolk sac
• the two endothelial cell layers are partially detached from the mesothelial and endodermal cell layers and the contacts of the two endothelial layers are not complete, resulting in distended capillary vessel formation
|
