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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Sle2NZM2410/Aeg
NZM2410/Aeg
MGI:2155957
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Sle2NZM2410/Aeg/Sle2NZM2410/Aeg involves: C57BL/6J * NZM2410/Aeg MGI:2175458
cx2
Sle1NZM2410/Aeg/Sle1NZM2410/Aeg
Sle3NZM2410/Aeg/Sle3NZM2410/Aeg
B6;NZM-Sle1NZM2410/Aeg Sle2NZM2410/Aeg Sle3NZM2410/Aeg/LmoJ MGI:3839653


Genotype
MGI:2175458
hm1
Allelic
Composition
Sle2NZM2410/Aeg/Sle2NZM2410/Aeg
Genetic
Background
involves: C57BL/6J * NZM2410/Aeg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sle2NZM2410/Aeg mutation (1 available); any Sle2 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• susceptibility to glomerulonephritis

renal/urinary system
• susceptibility to glomerulonephritis




Genotype
MGI:3839653
cx2
Allelic
Composition
Sle1NZM2410/Aeg/Sle1NZM2410/Aeg
Sle3NZM2410/Aeg/Sle3NZM2410/Aeg
Genetic
Background
B6;NZM-Sle1NZM2410/Aeg Sle2NZM2410/Aeg Sle3NZM2410/Aeg/LmoJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sle1NZM2410/Aeg mutation (2 available); any Sle1 mutation (2 available)
Sle2NZM2410/Aeg mutation (1 available); any Sle2 mutation (1 available)
Sle3NZM2410/Aeg mutation (1 available); any Sle3 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• increased proportion of B220+ CD1dhi splenic B cells
• impaired TI-2 antigen binding capacity
• increased intrafollicular localization of IgM+ CD1dhi B cells

immune system
• increased proportion of B220+ CD1dhi splenic B cells
• impaired TI-2 antigen binding capacity
• increased intrafollicular localization of IgM+ CD1dhi B cells





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory