mortality/aging

complete neonatal lethality ( J:75360 )

• affected animals die shortly after birth

craniofacial

cleft secondary palate ( J:75360 )

growth/size

decreased body length ( J:75360 )

• shortened body axis

respiratory system

respiratory failure ( J:75360 )

• likely leads to perinatal lethality

skeleton

absent proximal rib ( J:75360 )

• proximal portions of ribs are not present, causing a drastic size reduction of the chest

lordosis ( J:75360 )

• the lower cervical/upper thoracic region of the vertebral column are affected

abnormal vertebrae development ( J:75360 )

• abnormal ossification centers

digestive/alimentary system

cleft secondary palate ( J:75360 )

Mouse Models of Human Disease		OMIM ID	Ref(s)
Asphyxiating Thoracic Dystrophy 1; ATD1		208500	J:75360