Mouse Genome Informatics
hm1
    Ccw/Ccw
involves: unpedigreed stock
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
mortality/aging
• embryos die at the post-implantation stage


Mouse Genome Informatics
ht2
    Ccw/Ccw+
involves: unpedigreed stock
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
vision/eye
• at 4-6 weeks, the whole lens was degenerating
• at 14 weeks only a vestige, consisting of the lens capsule with some epithelial cells, remained
• lens fibers start to appear vacuolated at 10 days of age
• swollen and misshapen fibers were observed at 26 days of age
• first noticeable as a diffuse, cloudy lens at 3 weeks, progresses to total opacity by 5 weeks of age

integument
• the curly phenotype is mild; does not become apparent until 9-10 days of age