pigmentation
|
• the first coat is a uniform light tan
• at the first molt, the body hair becomes lighter, and the ears, nose, tail and scrotum become dark
• mutants treated with nitisinone show increased pigmentation in areas of new hair growth
|
|
• mutants exhibit iris transillumination that is not observed in wild-type mice
• mutants treated with nitisinone show increased pigmentation in the irides
|
|
• eyes are minimally pigmented and appear red
|
integument
|
• the first coat is a uniform light tan
• at the first molt, the body hair becomes lighter, and the ears, nose, tail and scrotum become dark
• mutants treated with nitisinone show increased pigmentation in areas of new hair growth
|
vision/eye
|
• mutants exhibit iris transillumination that is not observed in wild-type mice
• mutants treated with nitisinone show increased pigmentation in the irides
|
|
• eyes are minimally pigmented and appear red
|
Mouse Models of Human Disease |
OMIM ID | Ref(s) | |
| Albinism, Oculocutaneous, Type IB; OCA1B | 606952 | J:178454 | |
