Mouse Genome Informatics
hm1
    Lystbg-Lac/Lystbg-Lac
CBA/CaLac
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
craniofacial
• the ears are lighter than the expected agouti pigmentation

hearing/vestibular/ear
• the ears are lighter than the expected agouti pigmentation

limbs/digits/tail
• the tail is lighter than the expected agouti pigmentation

pigmentation
• the ears are lighter than the expected agouti pigmentation
• the coat appears grey on this agouti background
• the tail is lighter than the expected agouti pigmentation

integument
• the ears are lighter than the expected agouti pigmentation
• the coat appears grey on this agouti background
• the tail is lighter than the expected agouti pigmentation

growth/size
• the ears are lighter than the expected agouti pigmentation


Mouse Genome Informatics
hm2
    Lystbg-Lac/Lystbg-Lac
CBA/CaLac-Lystbg-Lac
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
hematopoietic system
• no evidence of NK cells is observed

immune system
• no evidence of NK cells is observed

cellular
• large granules like those associated with Chediak-Higashi Syndrome are observed

craniofacial
• pigmentation is reduced, much lighter than normal

hearing/vestibular/ear
• pigmentation is reduced, much lighter than normal

limbs/digits/tail
• pigmentation is reduced, appearing much lighter than normal

pigmentation
• pigmentation is reduced, much lighter than normal
• the coat appears grey on this background
• pigmentation is reduced, appearing much lighter than normal
• eyes are light at birth, varying from ruby to almost black in adults

vision/eye
• eyes are light at birth, varying from ruby to almost black in adults

integument
• pigmentation is reduced, much lighter than normal
• the coat appears grey on this background
• pigmentation is reduced, appearing much lighter than normal

growth/size
• pigmentation is reduced, much lighter than normal

Mouse Models of Human Disease
OMIM IDRef(s)
Chediak-Higashi Syndrome; CHS 214500 J:29745