Mouse Genome Informatics
hm1
     Lystbg-Lac/Lystbg-Lac
CBA/CaLac
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
craniofacial
decreased ear pigmentation ( J:29745 )
• the ears are lighter than the expected agouti pigmentation

hearing/vestibular/ear
decreased ear pigmentation ( J:29745 )
• the ears are lighter than the expected agouti pigmentation

limbs/digits/tail
decreased tail pigmentation ( J:29745 )
• the tail is lighter than the expected agouti pigmentation

pigmentation
decreased ear pigmentation ( J:29745 )
• the ears are lighter than the expected agouti pigmentation
diluted coat color ( J:29745 )
• the coat appears grey on this agouti background
decreased tail pigmentation ( J:29745 )
• the tail is lighter than the expected agouti pigmentation

integument
decreased ear pigmentation ( J:29745 )
• the ears are lighter than the expected agouti pigmentation
diluted coat color ( J:29745 )
• the coat appears grey on this agouti background
decreased tail pigmentation ( J:29745 )
• the tail is lighter than the expected agouti pigmentation


Mouse Genome Informatics
hm2
     Lystbg-Lac/Lystbg-Lac
CBA/CaLac-Lystbg-Lac
Key:
♀ phenotype observed in females WTSI Wellcome Trust Sanger Institute
♂ phenotype observed in males Euro Europhenome
N normal phenotype
hematopoietic system
absent NK T cells ( J:29745 )
• no evidence of NK cells is observed

immune system
absent NK T cells ( J:29745 )
• no evidence of NK cells is observed

cellular
abnormal lysosome morphology ( J:29745 )
• large granules like those associated with Chediak-Higashi Syndrome are observed

craniofacial
decreased ear pigmentation ( J:29745 )
• pigmentation is reduced, much lighter than normal

hearing/vestibular/ear
decreased ear pigmentation ( J:29745 )
• pigmentation is reduced, much lighter than normal

limbs/digits/tail
decreased tail pigmentation ( J:29745 )
• pigmentation is reduced, appearing much lighter than normal

pigmentation
decreased ear pigmentation ( J:29745 )
• pigmentation is reduced, much lighter than normal
diluted coat color ( J:29745 )
• the coat appears grey on this background
decreased tail pigmentation ( J:29745 )
• pigmentation is reduced, appearing much lighter than normal
abnormal eye pigmentation ( J:29745 )
• eyes are light at birth, varying from ruby to almost black in adults

vision/eye
abnormal eye pigmentation ( J:29745 )
• eyes are light at birth, varying from ruby to almost black in adults

integument
decreased ear pigmentation ( J:29745 )
• pigmentation is reduced, much lighter than normal
diluted coat color ( J:29745 )
• the coat appears grey on this background
decreased tail pigmentation ( J:29745 )
• pigmentation is reduced, appearing much lighter than normal

Mouse Models of Human Disease
 OMIM IDRef(s)
Chediak-Higashi Syndrome; CHS 214500 J:29745