Gt(ROSA)26Sor^{em1(CAG-Cdkl2)Bay}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(CAG-Cdkl2)Bay}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:8435602
• Synonyms: Rosa26-Cdkl2 OE
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(CAG-Cdkl2)Bay} page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: CPMM

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details:

  Using CRISPR/Cas9 genome editing in mouse embryos, a hybrid (CMV) enhancer and chicken beta-actin promoter (CBh) driving conditional expression of the mouse gene Cdkl2 with an upstream floxed stop cassette and downstream P2A-GFP fluorescent tag was inserted at the Gt(ROSA)26Sor locus. (J:358610)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1243 strains or lines available

References

• Original: J:358610 Baylor College of Medicine, Baylor College of Medicine Alleles. MGI Direct Data Submission. 2024
• All: 1 reference(s)