Rbm20^em1.1Schei
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbm20^em1.1Schei
• Name: RNA binding motif protein 20; endonuclease-mediated mutation 1.1, Peter Scheiffele
• MGI ID: MGI:8319095
• Gene: Rbm20 Location: Chr19:53665737-53855511 bp, + strand Genetic Position: Chr19, 48.28 cM
• Alliance: Rbm20^em1.1Schei page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted DNA sequences encoded a conditional by inversion (COIN) module, containing a 3'-splice site which allows the expression of the last exon of the gene fused to a histidin-biotin-histidin-tripleHA tag. The COIN allele is inserted in an orientation opposite to the genes direction of transcription. Activation by cre recombinase inverts the COIN module, resulting in splicing of the pre-mRNA to the tagged copy of the exon. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rbm20 Mutation: 58 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)