Spp1^em1Jeau
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spp1^em1Jeau
• Name: secreted phosphoprotein 1; endonuclease-mediated mutation 1, Jane E Aubin
• MGI ID: MGI:8317279
• Gene: Spp1 Location: Chr5:104582984-104588916 bp, + strand Genetic Position: Chr5, 50.68 cM
• Alliance: Spp1^em1Jeau page

Mutation origin

• Strain of Origin: (CD-1 x CD1;129-Ibsp^tm1Jeau/Jeau)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• TALEN-targeting of exon 5 generated a null allele. (J:382939)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spp1 Mutation: 45 strains or lines available

References

• Original: J:382939 Maalouf M, et al., Deletion of osteopontin or bone sialoprotein induces opposite bone responses to mechanical stimulation in mice. Bone Rep. 2022;17:101621
• All: 1 reference(s)