Sox2^tm1Asim
Targeted Allele Detail

Summary

• Symbol: Sox2^tm1Asim
• Name: SRY (sex determining region Y)-box 2; targeted mutation 1, Antonio Simeone
• MGI ID: MGI:8317188
• Synonyms: Sox2^deltaOBS
• Gene: Sox2 Location: Chr3:34704554-34706610 bp, + strand Genetic Position: Chr3, 16.93 cM, cytoband A2-B
• Alliance: Sox2^tm1Asim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutation: Nucleotide substitutions
• Mutation details: The targeting construct introduced a mutagenized version of the seven Otx2 binding sites (OBS) on Sox2 promoter in the region spanning to -4033 to -2408 respect to methionine 1. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox2 Mutation: 55 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)