Ngf^{tm2.1(NGF)Cat}
Targeted Allele Detail

Summary

• Symbol: Ngf^{tm2.1(NGF)Cat}
• Name: nerve growth factor; targeted mutation 2.1, Antonio Cattaneo
• MGI ID: MGI:8314886
• Gene: Ngf Location: Chr3:102377235-102428329 bp, + strand Genetic Position: Chr3, 45.25 cM
• Alliance: Ngf^{tm2.1(NGF)Cat} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Ngf^{tm2.1(NGF)Cat} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  NGF (4803)

  Ngf	(MGI:97321)

• Mutation details: The human NGF coding sequence and loxP flanked NeoR/KanR cassette and PGK promoter replaced the mouse coding sequence via homologous recombination. Cre-mediated recombination removed the selection cassette. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ngf Mutation: 14 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)