Impg1^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Impg1^tm1Ics
• Name: interphotoreceptor matrix proteoglycan 1; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:8282423
• Gene: Impg1 Location: Chr9:80220612-80347534 bp, - strand Genetic Position: Chr9, 43.99 cM
• Alliance: Impg1^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:378498
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 5 and an FRT site flanked neomycin resistance gene cassette followed by a second loxP site were inserted into intron 6. (J:378498)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Impg1 Mutation: 48 strains or lines available

References

• Original: J:378498 Olivier G, et al., SPACR Encoded by IMPG1 Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium. Genes (Basel). 2022 Aug 23;13(9)
• All: 1 reference(s)