Casp6^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Casp6^tm1.1Ics
• Name: caspase 6; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:8280973
• Gene: Casp6 Location: Chr3:129695074-129707752 bp, + strand Genetic Position: Chr3, 59.5 cM, cytoband H1
• Alliance: Casp6^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: P1 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron1 and a second loxP site and an FRT site flanked neomycin resistance gene cassette were inserted into intron 3. The neo cassette was removed through subsequent Flp-mediated recombination, leaving a conditional-ready allele with exons 2 (ENSMUSE00001243097) and 3 (ENSMUSE00001269048) (GRCm39, Casp6-201) floxed. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Casp6 Mutation: 16 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)