Tlr7^tm2.1Ics
Targeted Allele Detail

Summary

• Symbol: Tlr7^tm2.1Ics
• Name: toll-like receptor 7; targeted mutation 2.1, Mouse Clinical Institute
• MGI ID: MGI:8280962
• Gene: Tlr7 Location: ChrX:166087925-166113554 bp, - strand Genetic Position: ChrX, 78.31 cM, cytoband F5
• Alliance: Tlr7^tm2.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: S3 (ES Cell)
• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: IRES sequence plus mCherry reporter coding sequence were inserted after the stop codon in exon 3 (ENSMUSE00000690633), and an FRT site flanked neomycin resistance gene cassette site was inserted downstream of the gene. The neo cassette was removed through subsequent Flp-mediated recombination. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tlr7 Mutation: 26 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)