Sema3a^{em1(IMPC)Ccpcz}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sema3a^{em1(IMPC)Ccpcz}
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; endonuclease-mediated mutation 1, Institute of Molecular Genetics
• MGI ID: MGI:8261477
• Gene: Sema3a Location: Chr5:13175381-13652533 bp, + strand Genetic Position: Chr5, 4.31 cM
• Alliance: Sema3a^{em1(IMPC)Ccpcz} page
• IMPC: Sema3a gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Czech Centre for Phenogenomics using Cas9 and guides with spacer sequences ATAGACTAGTGACCTGGACC and ATGCTAGCTGAAGCACACTC that targeted exon(s) ENSMUSE00000183114.2. This resulted in deletion(s) of 45 bp (location: Chr5:13500772-13500816; GRCm39), 1376 bp (location: Chr5:13500821-13502196; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sema3a Mutation: 47 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)