Tbx15^em2H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tbx15^em2H
• Name: T-box 15; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:8250530
• Gene: Tbx15 Location: Chr3:99147697-99261575 bp, + strand Genetic Position: Chr3, 43.03 cM
• Alliance: Tbx15^em2H page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR/Cas9 mutagenesis introduced the nucleotide substitutions resulting in the amino acid substitution of histidine with asparagine at position 156 (H156N) and plus two silent changes. (J:361968)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Tbx15 Mutation: 50 strains or lines available

References

• Original: J:361968 Mary Lyon Centre at MRC Harwell, Direct data submission from Mary Lyon Centre at MRC Harwell. 2025
• All: 1 reference(s)