Gt(ROSA)26Sor^{tm2(CAG-tdTomato,-sr39tk)Feil}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(CAG-tdTomato,-sr39tk)Feil}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Robert Feil
• MGI ID: MGI:8243871
• Synonyms: Gt(ROSA)26Sor^{tm2(ACTB-tdTomato,-sr39tk)Feil}, sr39tk
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(CAG-tdTomato,-sr39tk)Feil} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:252312
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details:

  A loxP-flanked tdTomato reporter and a sr39tk PET reporter construct were inserted downstream of a CAG promoter at the Gt(ROSA)26Sor locus. The Tomato reporter is expressed until cre-mediated recombination removes the gene and allows the expression of the sr39tk reporter. (J:252312)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1243 strains or lines available

References

• Original: J:252312 Thunemann M, et al., Cre/lox-assisted non-invasive in vivo tracking of specific cell populations by positron emission tomography. Nat Commun. 2017 Sep 05;8(1):444
• All: 2 reference(s)