Gt(ROSA)26Sor^{tm23(UBC*)Ics}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm23(UBC*)Ics}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 23, Mouse Clinical Institute
• MGI ID: MGI:8238130
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm23(UBC*)Ics} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: BD10 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The following elements were inserted into an intron: an adenovirus splice acceptor site, a conditional STOP cassette (loxP site flanked cassette consisting of PGK promoter, neomycin resistance gene, PGK and 3x SV40 poly(A) signal sequences), followed by human UBC cDNA for the first 76 AAs with sequence coding for N-terminal histidine-biotin-histidine tag and bovine GH poly(A) signal sequences. The inserted gene will only be expressed after Cre-mediated removal of the STOP cassette. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1211 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)