Tg(Igfn1-EGFP)3H
Transgene Detail

Summary

• Symbol: Tg(Igfn1-EGFP)3H
• Name: transgene insertion 3, Harwell
• MGI ID: MGI:8237967
• Transgene: Tg(Igfn1-EGFP)3H Location: unknown
• Alliance: Tg(Igfn1-EGFP)3H page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: This IGFN1(D1-D3) transgene was designed to over-express a fragment of a large protein of unknown function (IGFN1), which exists in many different variants. IGFN1 was identified as an interacting partner to the KY protein, which is associated with a muscular dystrophy. The transgene contains only the first three domains of this protein fused to the fluorescent reporter GFP. It is expressed only in skeletal muscle. The purpose of this line was to test the effect of the overexpression and, on the other hand, cross it to the neuromuscular mutant ky and study possible genetic interactions. (J:361968)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:361968 Mary Lyon Centre at MRC Harwell, Direct data submission from Mary Lyon Centre at MRC Harwell. 2025
• All: 1 reference(s)