Wdr19^tm1Sji
Targeted Allele Detail

Summary

• Symbol: Wdr19^tm1Sji
• Name: WD repeat domain 19; targeted mutation 1, Si-Tse Jiang
• MGI ID: MGI:8216669
• Synonyms: Wdr19^f
• Gene: Wdr19 Location: Chr5:65357039-65417758 bp, + strand Genetic Position: Chr5, 33.58 cM
• Alliance: Wdr19^tm1Sji page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:368550
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JNarl

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details:

  The targeting cassette consisting of LoxP site, Wdr19 exons 4-36 cDNA, RFP, two polyA tails, FRT-flanked neomycin and loxP site replaced Wdr19 regions from exon 4 to exon 37 by homologous recombination. (J:368550)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr19 Mutation: 32 strains or lines available

References

• Original: J:368550 Yu SS, et al., Large deletion of Wdr19 in developing renal tubules disrupts primary ciliogenesis, leading to polycystic kidney disease in mice. J Pathol. 2022 May;257(1):5-16
• All: 1 reference(s)