Tatdn1^tm1.1Csaag
Targeted Allele Detail

Summary

• Symbol: Tatdn1^tm1.1Csaag
• Name: TatD DNase domain containing 1; targeted mutation 1.1, Daniel Sanchis
• MGI ID: MGI:8189913
• Synonyms: Tatdn1 loxP⁺
• Gene: Tatdn1 Location: Chr15:58762004-58805587 bp, - strand Genetic Position: Chr15, 25.09 cM
• Alliance: Tatdn1^tm1.1Csaag page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:365556
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT-flanked neomycin selection cassette and loxP site were inserted downstream of exon 3. The neomycin selection cassette was deleted via flp-mediated recombination, leaving exon 3 floxed. (J:365556)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tatdn1 Mutation: 18 strains or lines available

References

• Original: J:365556 Bares G, et al., Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis-responsive gene with roles in ventricular structure and neuromuscular function. FEBS J. 2025 Mar 23
• All: 1 reference(s)