Ccn1^tm1.1Alea
Targeted Allele Detail

Summary

• Symbol: Ccn1^tm1.1Alea
• Name: cellular communication network factor 1; targeted mutation 1.1, Andrew Leask
• MGI ID: MGI:8169041
• Gene: Ccn1 Location: Chr3:145352731-145355736 bp, - strand Genetic Position: Chr3, 70.18 cM
• Alliance: Ccn1^tm1.1Alea page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:364231
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129Sv/Pas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The target construct was designed to insert loxP sites flanking exon 2 of the cellular communication network factor 1 (Ccn1) gene. The construct also contained an FRT-flanked neomycin cassette upstream of the 3'loxP site. FLP-recombinase removed the neomycin cassette. (J:364231)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ccn1 Mutation: 35 strains or lines available

References

• Original: J:364231 Liu S, et al., CCN2 expression by fibroblasts is not required for cutaneous tissue repair. Wound Repair Regen. 2014 Jan-Feb;22(1):119-24
• All: 1 reference(s)