Tg(tetO-SLC13A5)1Lpu
Transgene Detail

Summary

• Symbol: Tg(tetO-SLC13A5)1Lpu
• Name: transgene insertion 1, Luigi Puglielli
• MGI ID: MGI:8161056
• Transgene: Tg(tetO-SLC13A5)1Lpu Location: unknown
• Alliance: Tg(tetO-SLC13A5)1Lpu page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Mutation: Insertion
• Tg(tetO-SLC13A5)1Lpu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SLC13A5 (284111)

  Slc13a5

  (MGI:3037150)

• Mutation details:

  The transgene over-expresses human SLC13A5 under the control of the pTRE-Tight vector (tetracycline) promoter. (J:341165)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:341165 Rigby MJ, et al., SLC13A5/sodium-citrate co-transporter overexpression causes disrupted white matter integrity and an autistic-like phenotype. Brain Commun. 2022 Feb;4(1):fcac002
• All: 2 reference(s)