Klk4^em1Odk
Endonuclease-mediated Allele Detail

Summary

• Symbol: Klk4^em1Odk
• Name: kallikrein related-peptidase 4 (prostase, enamel matrix, prostate); endonuclease-mediated mutation 1, Ophir D Klein
• MGI ID: MGI:7867415
• Gene: Klk4 Location: Chr7:43530584-43535228 bp, + strand Genetic Position: Chr7, 28.35 cM
• Alliance: Klk4^em1Odk page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: CRISPR/Cas-9 induced insertion of two loxP sites - one loxP site 213 base pairs upstream of ORF base position 1 in intron 1, and one loxP site 158 base pairs downstream of ORF base position 64 in intron 2 of the Klk4 gene on Chromosome 7. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Klk4 Mutation: 19 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)