Grin2b^em1Zuks
Endonuclease-mediated Allele Detail

Summary

• Symbol: Grin2b^em1Zuks
• Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2); endonuclease-mediated mutation 1, R Suzanne Zukin
• MGI ID: MGI:7867175
• Synonyms: NMDAR GluN2B Ser1166Ala
• Gene: Grin2b Location: Chr6:135690231-136150509 bp, - strand Genetic Position: Chr6, 66.38 cM
• Alliance: Grin2b^em1Zuks page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details: CRISPR-targeting introduced the mutation responsible for the amino acid substitution of serine with alanine at position 1166 (S1166A). (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grin2b Mutation: 100 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)