Gt(ROSA)26Sor^{tm2(CAG-IL37*G31V*T42A)Osjyz}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(CAG-IL37*G31V*T42A)Osjyz}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Yizu Jiao
• MGI ID: MGI:7865860
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(CAG-IL37*G31V*T42A)Osjyz} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: PRX-B6N (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(CAG-IL37*G31V*T42A)Osjyz} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  human	IL37 (27178)

• Gt(ROSA)26Sor^{tm2(CAG-IL37*G31V*T42A)Osjyz} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: The targeting construct introduced into the locus human IL37 with amino acid substitutions G31V and T42A. (J:94077, J:268128)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)