Tg(Csf1r-EGFP/Rpl10a)1Glass
Transgene Detail

Summary

• Symbol: Tg(Csf1r-EGFP/Rpl10a)1Glass
• Name: transgene insertion 1, Christopher Glass
• MGI ID: MGI:7863630
• Synonyms: Csf1r-EGFP-L10
• Transgene: Tg(Csf1r-EGFP/Rpl10a)1Glass Location: unknown
• Alliance: Tg(Csf1r-EGFP/Rpl10a)1Glass page

Transgene origin

• Strain of Origin: C57BL/6NHsd

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Tg(Csf1r-EGFP/Rpl10a)1Glass expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Csf1r (MGI:1339758)

• Mutation details: The EGFP-L10alpha construct was then cloned downstream of the c-fms promoter. The EGFP-L10alpha fusion protein is constitutively expressed in myeloid cells. The expression of EGFPL10alpha allows to specifically immunprecipitate polysome bound mRNA in myeloid cells. (J:361674)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:361674 Shibata N, et al., 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages. J Biol Chem. 2013 Dec 13;288(50):35812-23
• All: 2 reference(s)