Pkhd1^em4H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pkhd1^em4H
• Name: polycystic kidney and hepatic disease 1; endonuclease-mediated mutation 4, Harwell
• MGI ID: MGI:7863627
• Gene: Pkhd1 Location: Chr1:20128003-20688288 bp, - strand Genetic Position: Chr1, 6.27 cM, cytoband A2-A5
• Alliance: Pkhd1^em4H page

Mutation origin

• Strain of Origin: C3H/HeH

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation
• Mutation details:

  This is a CRISPR/Cas9 induced mutation creating point mutation T37M in exon ENSMUSE00001279293 of Pkhd1 via microinjection of CRISPR/Cas9 reagents into 1-cell stage embryos. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pkhd1 Mutation: 228 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)