Hprt1^{tm1(CAG-cre,-flpo,-EYFP)Ics}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm1(CAG-cre,-flpo,-EYFP)Ics}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:7863540
• Synonyms: Hprt1^{tm1(CAG-cre/flpo/EYFP)Ics}
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm1(CAG-cre,-flpo,-EYFP)Ics} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/cN

Mutation description

• Allele Type: Targeted (Conditional ready, Recombinase, Reporter)
• Mutation: Insertion
• Hprt1^{tm1(CAG-cre,-flpo,-EYFP)Ics} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: This allele contains a CAG-cre-2A-flpo-2A-EYFP cassette with an inserted roxed selection (NeoR) cassette and is located in the Hprt1 gene on the X chromosome. Maternal contribution observed when used as a cre deleter. Both cre and flpo recombinases are active but cre-mediated excision occurs first when bred with lines containing both floxed and flipped sequences. (J:82809)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1278 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)