Bcar1^tm1.1Scbd
Targeted Allele Detail

Summary

• Symbol: Bcar1^tm1.1Scbd
• Name: breast cancer anti-estrogen resistance 1; targeted mutation 1.1, Sara Cabodi
• MGI ID: MGI:7861825
• Gene: Bcar1 Location: Chr8:112437106-112470441 bp, - strand Genetic Position: Chr8, 57.98 cM, cytoband D3
• Alliance: Bcar1^tm1.1Scbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:316303
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct floxed exons 5 adn 6. Flp-mediated recombination removed the selection cassette. (J:316303)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bcar1 Mutation: 27 strains or lines available

References

• Original: J:316303 Camacho Leal MDP, et al., Conditional ablation of p130Cas/BCAR1 adaptor protein impairs epidermal homeostasis by altering cell adhesion and differentiation. Cell Commun Signal. 2018 Nov 3;16(1):73
• All: 2 reference(s)