Gfm1^em1Rmrt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gfm1^em1Rmrt
• Name: G elongation factor, mitochondrial 1; endonuclease-mediated mutation 1, Ramon Marti
• MGI ID: MGI:7858914
• Gene: Gfm1 Location: Chr3:67337448-67382401 bp, + strand Genetic Position: Chr3, 30.96 cM
• Alliance: Gfm1^em1Rmrt page

Mutation origin

• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 and 3. (J:361430)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gfm1 Mutation: 34 strains or lines available

References

• Original: J:361430 Molina-Berenguer M, et al., Dysfunctional mitochondrial translation and combined oxidative phosphorylation deficiency in a mouse model of hepatoencephalopathy due to Gfm1 mutations. FASEB J. 2022 Jan;36(1):e22091
• All: 1 reference(s)