Chd8^tm2.1Csbd
Targeted Allele Detail

Summary

• Symbol: Chd8^tm2.1Csbd
• Name: chromodomain helicase DNA binding protein 8; targeted mutation 2.1, Eunjoon Kim
• MGI ID: MGI:7857151
• Synonyms: Chd8^fl
• Gene: Chd8 Location: Chr14:52435608-52495237 bp, - strand Genetic Position: Chr14, 26.84 cM
• Alliance: Chd8^tm2.1Csbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:304308
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The gene was flanked by loxP sites, an frt-flanked neomycin-resistance cassette and an EGFP gene. The cassette was removed by Flp expression in the germline. (J:304308)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chd8 Mutation: 108 strains or lines available

References

• Original: J:304308 Kweon H, et al., Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors. Cell Rep. 2021 Feb 23;34(8):108780
• All: 1 reference(s)