Tg(CD2-Egr2)14Pwg
Transgene Detail

Summary

• Symbol: Tg(CD2-Egr2)14Pwg
• Name: transgene insertion 14, Ping Wang
• MGI ID: MGI:7857118
• Synonyms: CD2-Egr2-Tg
• Transgene: Tg(CD2-Egr2)14Pwg Location: unknown
• Alliance: Tg(CD2-Egr2)14Pwg page

Transgene origin

• Strain of Origin: (C57BL/6 x CD1)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD2-Egr2)14Pwg expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Egr2 (MGI:95296)

• Tg(CD2-Egr2)14Pwg expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  CD2 (914)

  Cd2	(MGI:88320)

• Mutation details: The transgene contains the human CD-2 promoter, hCD2 LCR, Egr-2 cDNA, and poly-A signal. Lines 14 and 18 were generated, both with high expression. Line 14 was selected as the representative line. (J:172386)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:172386 Li S, et al., Early growth response gene-2 (egr-2) regulates the development of B and T cells. PLoS One. 2011;6(4):e18498
• All: 2 reference(s)