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Tg(CD4-Tcra,CD4-Tcrb)2Bnlt
Transgene Detail
Summary
Symbol: Tg(CD4-Tcra,CD4-Tcrb)2Bnlt
Name: transgene insertion 2, Bart Lambrecht
MGI ID: MGI:7856671
Synonyms: 1-DER
Transgene: Tg(CD4-Tcra,CD4-Tcrb)2Bnlt  Location: unknown  
Alliance: Tg(CD4-Tcra,CD4-Tcrb)2Bnlt page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailscDNAs encoding productively rearranged V4 and V4 chains were cloned from a Derp-1-specific hybridoma cell line. The TCRV and V cDNAs were cloned into human CD4 promoter with silencer and human CD4 promoter expression vectors. (J:233389)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:233389 Coquet JM, et al., Interleukin-21-Producing CD4(+) T Cells Promote Type 2 Immunity to House Dust Mites. Immunity. 2015 Aug 18;43(2):318-30
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory